重组人IL-19

产品货号：

GS4536

中文名称：

重组人IL-19

英文名称：

Recombinant Human Interleukin-19

产品规格：

2μg

发货周期：

1～3天

产品价格：

询价

分子量：Approximately 17.9kDa,a single non-glycosylated polypeptide chain containing 153 amino acids.
储存条件：冷冻（-20℃）

概述

Human Interleukin-19(IL-19)is encoded by the IL19 gene,which is located on the chromosome 1.The protein belongs to the IL-10 family that includes IL-10,IL-20,IL-22,IL-24,and IL-26.As a monomer made of seven amphipathic helices,IL-19 has a helical bundle and shares the same cell surface receptor(IL-20R)with IL-20 and IL-24.It may play some important roles in inflammatory responses because it up-regulates IL-6 and TNF-alpha and induces apoptosis.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using human IL-20Rα and human IL-20Rβ co-transfected murine BaF3 pro-B cells is less than 1.5ng/ml,corresponding to a specific activity of>6.7×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1EU/μg of rHuIL-19 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	LRRCLISTDM HHIEESFQEI KRAIQAKDTF PNVTILSTLE TLQIIKPLDV CCVTKNLLAF YVDRVFKDHQ EPNPKILRKI SSIANSFLYM QKTLRQCQEQ RQCHCRQEAT NATRVIHDNY DQLEVHAAAI KSLGELDVFL AWINKNHEVM SSA

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